系统性红斑狼疮相关实验室检查结果分析

RELATED LABORATORY RESULTS OF SYSTEMIC LUPUS ERYTHEMATOSUS

目的 通过对系统性红斑狼疮 (SLE)患者实验室检查结果的分析来探讨临床早期诊断的指标。方法 回顾性对 57例SLE患者的血液学特别是ANA ,抗ds-DNA及ENA谱测定结果与正常对照组进行分析。结果 SLE贫血最常见占 73 .7%。ANA阳性占96 .5 % ,抗ds -DNA阳性占 57.9% ,ENA阳性占 66 .7%。而正常对照组均为 0 % (P <0 .0 1 )。结论 血液学及几种自身抗体检测异常对该病早期诊断及鉴别诊断 ,病情监测 。

Objective To approach the laboratory targets for clinical earlier period diagnosis. Methods Antinuclear antibody(ANA), anti-double-stranded DNA antibody(anti-ds DNA) and EAN-Stectrum of blood samples of 57 cases with systemic lupus erythematosus(SLE) were detected, and the detected results were retrospectly analyzed. Results Anemic of SLE occurred most commonly, occupied 73.7%, ANA positive occupied 96.5%, anti-ds-DNA positive occupied 57.9%, EAN positive occupied 66.7%. But the normal matched control was all occupied 0%(P<0.01). Conclusion Hematology and antibody examine take an important role in diagnosis, condition monitor and efficiency observation.