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小儿病毒性肝炎患者IL-10、IL-2、SIL-2R水平及其相关性 被引量:2

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摘要 目的:进一步探讨血清白细胞介素-10(IL-10),白细胞介素-2(IL-2),可溶性白细胞介素-2受体(SIL-2R)在小儿病毒性肝炎患者中的水平及其相关性。方法:采用ELISA(免疫酶标法)对57例小儿病毒性肝炎患者的IL-2、SIL-2R、IL-10进行了测定。结果:在慢性轻度组血清IL-10水平显著降低(P<0.05);其中急性肝炎组和慢性重型组血清IL-10水平变化不大,IL-2与SIL-2R在各类型小儿肝炎中都显著高于对照组(P<0.05),其中,IL-2在急性肝炎中升高最为显著,SIL-2R在慢性重型肝炎组中升高最为显著.IL-2和SIL-2R与IL-10的水平负相关。结论:检测血清IL-2、SIL-2R、IL-10在判断小儿病毒性肝炎患者肝脏损害程度上有一定的价值,对重型肝炎的预后有一定意义。
出处 《世界感染杂志》 2003年第4期300-301,共2页 World Journal of Infection
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参考文献7

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