超液化碘油混合抗癌药物栓塞治疗中晚期肝癌

Transcatheter Arterial Embolization Using Lipiodol Ultra-fluid Mixed with Chemotherapeutical agent for the Treatment of Hepatocellular Carcinoma

本文报告超液化碘油混合抗癌药物经皮肝动脉栓塞治疗51例中晚期肝癌。术后50例临床病情改善,治疗2次后肿瘤显著缩小(>50%)16例,中度缩小(20～50%)21例,轻度缩小(<20%)7例;5例为弥漫型难以判定肿块大小,另2例未复查。所有肿瘤缩小的病例均可见肿瘤血管减少。治疗后3个月、6个月、9个月和1年以上生存率分别为100%、82.4%、59.8%和23.5%,其中生存期大于9个月者均为团块型或多结节型。

146 times of transcatheter hepatic aterial embolization using lipiodol ultra-fluid mixedwith chemotherapeutical agent were performed on 51 patients(47 primary and 4 secondary hepatocellularcarcinoma).The results showed that:(1)The marked diminution of tumor size(>50%)was found in31.4% of patients(16/51),moderate diminution(20～50%)in 41.2%(21/51)and slight diminution(<20%)in 17.3%(7/51);(2)The survivalrates were 100% for 3 months,82.4% for 6 months.59.8% for 9 months and 23.5% for 12 months or more.These results showed that it is one of theeffective non-surgical treatment of hepatocellular carcinoma.