曲马多、安得返术后镇痛效果观察

A clinical Study on the Postoperative Analgesic Effects of Tramal and Artiflam

本文观察比较60例妇科术后患者肌注曲马多100mg或安得返200mg的镇痛效果,并与肌注哌替啶50mg作对照。患者随机分为三组,结果显示各组的可比性较好。注药后30min的镇痛强度顺序是哌替啶>曲马多>安得返,但组间差异无统计学意义。在用药次数、镇痛维持时间、夜间睡眠质量和病人评价等方面均以曲马多为最佳。副作用以哌替啶组最多,安得返组最少。由于曲马多和安得返无成瘾性,安全性大,可反复用药或加大药量以提高不敏感者的镇痛效果,建议将它们列为术后镇痛的一线药物。

The analgesic effects of 100mg Tramal and 200mg Artiflam given intramuscularly to postoperative gynecologic patients respectively were investigated and compared with the 50mg Pethitine as a control agent. 60 cases were divided into 3 groups. The analgesic intensity was Pethitine>Tramal>Artiflam whichwas evaluated 30 minutes after their administration. No statistically differences among the 3 groups were found. According to the patients'evelvation Tramal is the best in night sleep;Artflam has the least side effects.