重评灭吐灵对阑尾牵拉反应的影响

Reevaluting the Effect of Paspertin on Traction Reactions of Appendectomy

本文重新评价了灭吐灵对阑尾牵拉反应的影响。选90例阑尾切除术患者,随机分为三组。结果:对照组牵拉反应达O～Ⅰ级者占10%,哌替啶组占47.5%,而灭吐灵组采取灭吐灵改为术前用药替代阿托品,并用较大剂量(20～40mg)及提前给药(处理阑尾前30min)的方法,牵拉反应达O～Ⅰ级者占93。3%,与哌替啶组相比有非常显著的差异(P<0.01)。

90 patients udergoing appendectomy were randomly divided into three groups, control group(n=20),pethi- dine group(n=30,pethidine Img/kg before incisiom) ,and paspertin group (n =30,paspertin 20～40mg Ⅳ 30 min- utes before appendix traction). The results showes that in the control group ,the rate of 0-Ⅰ traction reactions was 10% ,pethidine group 47.5% , and paspertin group 93. 3%(P<0.01). It is concluded that paspertin might ef- fectively inhibit traction reaction during appendectomy.