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城镇人群1194例HP尿素酶抗体测定对HP流行病学的研究 被引量:1

Seroepidemiological Study of Helicobacter Pylori in 1194 Cases of Cities and Towns Detecting Anti--urease Antibody
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摘要 以6株幽门螺杆菌(HP)尿素酶作为抗原,用间接酶联免疫法(ELISA)检测城镇人群1194例HP感染的流行病学调查。结果:该试验敏感性为90%,特异性为90%;HP感染率为40.2%,并随年龄增长而增加;有上消化道症状的HP感染率明显高于无症状者(P<0.05)。其感染率与性别、职业、地区分布、血型和个人烟酒嗜好无关。 The urease extract of Helicobacter pylori (HP) was used as antigen to detect sera anti-urease antibodies of HP in 1194 cases of cities and towns by ELISA for the epidemiological study of HP infection. The results showed that sensitivity and specificity were 90% respectively, the HP infection rate was 40.2% and was increased with age and was higher (P<0.05) among persons with upper gastrointestinal symp- toms than without those symptoms. HP infection had no relation to sexes, occupation, blood types, regions, smoking and drinking.
出处 《临床消化病杂志》 1993年第2期49-51,共3页 Chinese Journal of Clinical Gastroenterology
关键词 幽门螺杆菌 流行病学 尿素酶 抗体 Hellcobacter pylori (HP) Epidemiology Anti-urease antibody
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