51例胸腹水中细胞AgNOR定量研究

A QUANTITATIVE STUDY OF AGNOR IN THE CELLS IN THE PLEURAL EFFUSION AND ASCITES FROM FIFTY-ONE PATIENTS

51例胸腹水中细胞AgNOR染色后显示,AgNOR颗粒均值分别为腺癌(19例)8.99±2.31;未分化癌(4例)7.24±1.40;恶性肿瘤(未分类,3例)9.16±1.10;间皮瘤(2例)12.73±1.61;白血病浸润(2例)4.21±0.64;正常淋巴细胞(51例)2.01±0.28;正常间皮细胞(51例)2.81±0.32。恶性肿瘤细胞与非肿瘤细胞AgNOR颗粒数量有显著性差异(P<0.001),而且颗粒的分布及形态亦不相同。证明AgNOR染色对鉴别良恶性胸腹水有重要价值。

After the cells in the pleural effusion and ascites from 51 patients were stained.we found that the numbers of AgNOR averaged: adenocarcinoma, (19 cases)8.99±2.31; undifferentiated carcinoma, (4 cases)7.24±1.40;the malignant tumours which were not classified, (3 cases)9.16±1.10;mesothelioma, (2 cases)12.73±1.61;leukemic infiltration,(2 case)4.21±0.64;the normal lymphocytes, (51 cases) 2.01±0.28;and the normal mesothelial cells,(51 cases)2.81±0.32. There was a marked difference in the numbers of AgNOR between the malignant tumour cells and the nontumorous cells (P<0.001). The distribution and shape of AgNOR were also different. It is proved that the staining of AgNOR is of great value in discriminating the benign and malignant pleural effusion and ascites.