微波辐射下“一锅煮”法合成2-氨基-3-氰基-4-芳基-4H,5H-吡喃-[3,2-c]苯并吡喃-5-酮

An Efficient One-Pot Synthesis of 2-Amino-3-cyano-4-aryl-4H,5H- pyrano[3,2-c]benzo[b]pyran-5-one under Microwave Irradiation

以芳醛、4 羟基香豆素、丙二腈为原料 ,乙醇为能量转移剂 ,哌啶为催化剂 ,在微波辐射下一步合成了一系列 2 氨基 3 氰基 4 芳基 4H ,5H 吡喃 [3 ,2 c]苯并吡喃 5 酮 ,反应在 40～ 60s时间内完成 ,产率 60 %～ 97% .

A series of 2-amino-3-cyano-4-aryl-4H, 5 H-pyrano[3,2-c] benzo [b] pyran-5-ones were synthesized by the reaction of 4-hydroxycoumarin, aromatic aldehydes and malononitrile using piperidine as catalyst, ethanol as energy transfer agent under microwave irradiation.