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牛血清蛋白单层膜诱导形成网状结构的羟基磷灰石 被引量:8

Synthesis of a Network Structure Hydroxyapatite by Bovine Serum Albumin Monolayer Induction
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摘要 LB (Langmuir-Blodgett) technology was used to prepare the BSA monolayers m ore closely related to the half-layer biological membrane structure. The influen ce of bovine serum albumin (BSA) was studined on the polymorph, morphology and g rowth orientation of hydroxyapatite in the process of the biomineralization. XRD and SEM were respectively used to analysis the polymorph and morphology of the crystal induced by BSA monolayers. The results of XRD show that the HAP grows on ly along the (112) face, indicating a well oriented face in HAP. In addition, SE M shows that the morphologies of the HAP is of a network structure. In conclusio n, when the BSA form monolayers, it can be used as a template to induce the HAP to crystallize. Accordingly, the monolayers of the protein can be used to induce the inorganic materials to grow with a complex morphology and a well oriented f ace by biomimetic approach. LB (Langmuir-Blodgett) technology was used to prepare the BSA monolayers more closely related to the half-layer biological membrane structure. The influence of bovine serum albumin (BSA) was studined on the polymorph, morphology and growth orientation of hydroxyapatite in the process of the biomineralization. XRD and SEM were respectively used to analysis the polymorph and morphology of the crystal induced by BSA monolayers. The results of XRD show that the HAP grows only along the (112) face, indicating a well oriented face in HAP. In addition, SEM shows that the morphologies of the HAP is of a network structure. In conclusion, when the BSA form monolayers, it can be used as a template to induce the HAP to crystallize. Accordingly, the monolayers of the protein can be used to induce the inorganic materials to grow with a complex morphology and a well oriented face by biomimetic approach.
出处 《无机化学学报》 SCIE CAS CSCD 北大核心 2004年第12期1426-1428,共3页 Chinese Journal of Inorganic Chemistry
基金 国家自然科学基金资助项目(No.90306010 20371015) "973"前期专项资助课题(No.2002CCC02700)
关键词 牛血清蛋白 单层膜 网状结构 羟基磷灰石 生物矿化 取向生长 陶瓷薄膜 仿生合成 生物材料 bovine serum albumin calcium hydroxyapatite biomineralizat ion oriented growth
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参考文献12

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