经颅磁刺激系统各主要参数实现的量化设计

Quantitative design of the primary parameters of transcranial magnetic stimulation system

目的:设计和实现符合实验要求的经颅磁刺激系统,并对磁刺激系统的各主要参数进行量化研究。方法:利用储存电能的电容器对线圈放电产生强脉冲磁场的原理,设计了磁刺激系统的电源电路和刺激线圈,并利用单片机实现了对电路的控制。测量磁刺激系统的感应电场分布等主要参数,进行了量化研究。结果:分别对圆形线圈和八字线圈进行了测试。其中圆形线圈的内外半径各为1cm和5cm,共20匝,电感为21.5μH,电阻为12.8mΩ。八字线圈的内外半径各为3.5cm和5cm,一个线圈有7匝,电感为17μH,电阻为24.6mΩ。实际测试结果与仿真计算结果都表明,作者设计的磁刺激系统各项指标均满足经颅磁刺激实验研究的要求。结论:该套经颅磁刺激系统可应用于临床应用研究和生物学实验研究。

AIM:To design and realize a system of transcranial magnetic stimulation(TMS) meeting the requirements of the experiment, and study quantitatively the primary parameters of the system. METHODS: The power circuit of the system and the stimulating coil were designed by using the principle that strong magnetic field will be produced when the coil is driven by capacitor discharge, and the controlling system was realized with singlechip. The primary parameters, such as the distribution of electric field were measured and studied quantitatively. RESULTS: The round coil and splayed coil were tested respectively. For the round coil, the inner and outer radii were 1 and 5 cm respectively, the coil consisted of 20 conbolutions, inductance was 21.5 μH and resistance was 12.8 mΩ. For the splayed coil, the inner and outer radii were 3.5 and 5 cm respectively, 1 coil consisted of 1 conbolutions, inductance was 17 and resistance was 24.6 mΩ. The results of actual test and stimulation calculation showed that the parameters of this system met the requirements of the TMS. CONCLUSION:The TMS can be used for clinical application and biological experiments.