羟基磷灰石涂层的氧化锆陶瓷骨内种植实验初步研究

An experimental study on the HA-coated zirconia ceramic material for an endosseous implant

将烧结涂层的羟磷灰石－氧化锆复合生物陶瓷种植体及纯钛种植体按低创伤手术原则植入犬股骨。三个月后取标本进行骨一种植体结合强度试验，作含复合陶瓷种植体的不脱钙组织切片光镜观察、扫描电镜观察及Ｃａ、Ｐ、Ｚｒ元素探针检测分析，结果表明，复合陶瓷－骨结合强度，显著高于钛－骨结合强度；复合陶瓷与骨组织结合紧密，界面无纤维结缔组织间隔，说明该材料具有极好的生物相容性。考虑到氧化锆陶瓷有着优良的机械性能，预计该复合生物陶瓷材料可能具有良好的发展前景。

HA layer is sintered onto the surface of zirconia ceramic material. These column-like composite implants and titanium implants were inserted into the femurs of the dogs.The specimens were taken at the third month after operation, and the shear strengs between the implants and bone were measured.The undecalcified bone section containing the composite ceramic implant were cut for light microscopy, scanning electron microscopy and elemental analyses of C, P and Zr. Mechanical testing results revealed that the attachment strength of HA-coated zirconia samples is more stronger, as companied with the titanium samples. Histologie evaluations of the undecalcified specimens showed that extremely close juxlaposition of bone to HAcoated zirconia ceramic implants was seen.