脑胶质瘤瘤周水肿机制及临床意义

Study on Mechanism of Peritumoral Edema of Brain Gliomas and Clinical Significance

对１４例脑胶质瘤的瘤体、水肿带和正常脑组织进行对照电镜研究，结果表明脑水肿产生是瘤体和瘤周血脑屏障破坏的结果。前者是先决因素，细胞毒起重要作用。血脑屏障变化的程度与瘤周水肿相一致。

Patients with brain gliomas were studied with transmission electron microscope(TEM),with comparing analysis of ultrstucture during tumor,edema area and normal brain tissues.The results demonstrate that brain edema was the result with structural changes of tumoral and peritumoral blood-brain-barrier(BBB).It was the major factor causing disturbance of BBB. However,cytotoxic edema plays an important rolealso.The more abnormality of BBB existed,the more edema were found.