益气活血治法实验研究（Ⅱ）

^The Experimental Research on Tonifying Qi andActivating Blood Circulation Method

单味黄芪和地龙煎剂均可明显使体外血栓长度、湿重、干重减少，抑制红细胞聚集，降低血浆纤维蛋白原含量。地龙煎剂尚可明显降低各切交率下的全血粘度，改善红细胞的变形能力。但单味黄芪和地龙煎剂均无抑制血小板聚集作用。而黄芪地龙合剂除明显改善血流变各项特性、抗血栓作用外，对血小板聚集也有明显的抑制作用。黄芪、地龙配伍使用呈现的基本协同效应，说明了益气活血配伍的合理性。

he decoctions of Astraglus Root. Allolobophora Caliginosa and their mixture are adiministrated to the old animalmodel with Qi deficiency and blood stasis syndorme in this experiment. The hemorrheological signs and thrombosis invitro are observed. The results showed that both single Astraglus Root and single Allolobophora Caliginosa decoctioncould markedly reduce the length, wet weight. dry weight of thrombosis in vitro. inhibit RBC aggregation and decreasethe plasma fibrenogen concentration. The decoction of Allolobophora Caliginosa can still significantly decrease wholeblood viscosity at all kindS of shear and improve RBC deformability. But neither Allolobophora Caliginosa nor Astraglus Root inhibited platalet aggregation. Addition to that it can improve every hemorrheogical signs and resistthrombosis in vitro. the decoction of Astraglus Root and Allolobophora Caliginosa can markedly inhibit the platalet aggregation. That compatibility of Astraglus Root with Allolobophora Caliginosa presents replenishment effect each othercan further explain the rationalization of compatibility of Tonifying Qi and Activating Blood Circulation herbs.