缺血性中风血液流变学及高凝状态的临床分析

A Clinical Analysis of the Hemorheology and Blood Hypercoagulable State in Ischemic Stroke

通过对８７例缺血性中风患者治疗前后血液流变学及１２项血凝学指标的对比研究，发现缺血性中风患者同时存在高粘滞血症及血液高凝状态，两者均为中风危险因素，且互为因果。建议将部分血凝学指标列为中风危险因素分析内容之一；在治疗高粘滞血症同时，积极纠正血液高凝状态。

This paper presents 87 cases of ischemic stroke and 90 healthy control subjects.We made a comparative study on 5 items in hemorheology (including Hct,MAR,ESR,etc.)and 7 items in blood coagulation system(including AT-Ⅲ,ⅧR:Ag,etc.)of the two groups,Moreover,we treated the 87 patients with the method of hypervolemic hemodilution, and studied the changes of these items before and after the treatment.the results showed that the patient group had significantly different results from those of the control group (P<0.001). After the treatment, most of the hemorheological items of the patient group were significantly improved while most of the items in blood coagulation system remained unchanged. It was found that most patients suffered from hyperviscosaemia and hypercoagulative state simultaneously.Both of the states were risk factors to stroke.They were correlated. Therefore.it is suggested that the changes of AT-Ⅲ,ⅧR:Ag,etc.should be enlisted in the contents of stroke risk factor anslysis.While hyperviscosaemia is treated, hypercoagulative state should also be corrected.