伐地那非治疗抑郁症合并勃起功能障碍的有效性和安全性

Efficacy and Safety of Vardenafil in Men with Erectile Dysfunction and Depression

勃起功能障碍 (erectiledysfunction ,ED)与抑郁症常合并存在 ,两者可相互恶化 ,给患者带来更大的痛苦 ,因而更加需要迫切、有效的治疗方法。最近的DRIVER(DepressionRelatedImprovementwithVardenafilforErectileResponse)试验结果表明 ,磷酸二酯酶 5 (PDE5 )抑制剂伐地那非不仅能改善ED合并抑郁症男性的勃起功能 ,而且能减轻抑郁症状 ,改善生活质量 ;且使用安全 ,耐受性好。

Erectile dysfunction (ED) usually exists in combination with depression in men. The comorbidity of the two diseases may bring more troubles to patients, so it is important to find an effective treatment. Recently, DRIVER(Depression Related Improvement with Vardenafil for Erectile Response)trials showed that, phosphodiesterase 5 (PDE 5) inhibitor vardenafil could improve not only erectile function but also depressive symptoms and quality of life in men with ED and depression. Vardenafil was generally safe and well tolerated.