1[1]Ali S, Mann DA. Signal transduction via the NF- kappaB pathway: a targeted treatment modality for infection, inflammation and repair[J] .Cell Biochem Funct,2004,22(2):67- 79.
2[2]Li ZW, Chu W, Hu Y, et al. The IKKbeta subunit ofIkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis[J]. J Exp Med,1999,189:1839- 1845
3[3]Rayet B, Gelinas C. Aberrant rel/nfkb genes and activity in human cancer[J]. Oncogene,1999,18(49): 6938-6947.
4[4]ChenF, Fischle W, Verdin E, et al. Duration of nuclear NF- κB action regulated by reversible acetylation[J] .Science, 2001,293(5535): 1653
5[5]Fan J, Ye RD, Malik AB. Transcriptional mechanism of acute lung injury[J]. Am J Physiol Lung Cell Mol Physiol,2001,281(5): L1037 - L1050.
6[6]Klinkenberg M, Van Huffel S, Heyninck K, et al.Functional redundancy of the zinc fingers of A20 for i.nhibition of NF- kappaB activation and protein - protein interactions[J] .FEBS Lett,2001,498( 1 ) :93 - 97.
7[7]Tasaka S, Ishizaka A, Yamada W, et al. Effect of CD14 blockade endotoxin- induced acute lung injury in mice[J] .Am J Respir Cell Mol Biol,2003 ,29(2) :252 - 258.
8[8]Akashi S, Shimazu R, Ogata H, et al. Cutting edge: cell surface expression and lipopolysaccharide signaling via the toll - like receptor 4 - MD - 2complex on mouse peritoneal macrophages[J].J Immunol, 2000,164(7):3471-3475.
9[9]Hatada EN, Krapp mann D, Scheidereit C. NF- kappaB and the innate immune response[J]. Curr Opin Immanol,2000,12(1) :52- 58.
10[10]Nakano H, Shindo M, Sakon S, et al. Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF kappaB - inducing kinase and mitogen - activated protein kinase/ERK kinase kinase - 1 [J].Proc Natl Acad Sci USA, 1998, 95: 3537- 3542.
二级参考文献35
1Woronic JD, Gao X, Cao E, et al. Iκ B kinase-β NF-κ B activation and complex formation with I κ: B kinase-α and NIK Science, 1997,278 : 886-869.
2Bernard GR, Artigas A, Brigham KL, et at. Report of the American-European consensus conference on ARDS: definitions, mechanisms,relevant outcomes, and clinical trial coordination. Intensive Care Med,1994, 20: 225-236.
3Tak PP, Fireslein GS. NF-kappaB: a key role in inflammalory disease. J Clin Invest, 2001, 107: 7-11.
4Ghosh S, Latimer RD, Gray BM, et al. Endotoxin-induced organ injury. Crit Care Med, 1993, 21: S19-24.
5Marsh CB, Wewer MD, The pathogenesis of sepsis: factor that modulate the response to gram-negative bacterial infection. Clin Chest Med,1996, 17: 183-197.
6Allen JN, Herzyk DJ, Allen ED, et al. Human Whole blood interleukin-1β production: kinetics, Cell source and comparison to TNFα. J Lad Clin Med, 1992, 119: 534-546.
7Baldwin AS. Series introduction: the transcription factor and human disease. J Clin Invest, 2001, 107: 3-6.
8Rahman I, MacNee W. Role of transcription factor in inflammatory lung disease. Thorax. 1998, 53: 601-612.
9Bohrer M, Qiu F, Zimmerman T, et al. Role of NF-κ B in the mortality of sepsls. J Clin Invest, 1997, 100: 927-985.
10Kawai T;Adachi O;Ogawa T.Unresponsiveness of MyD88-deficient mice to endotoxin[J],1999(1).
