老年高血压病患者大动脉扩张性的临床研究

Clinical study of the distcnsihilily of large arteries in eldcrly patients with essential hypertension

目的 探讨老年高血压病患者大动脉扩张性的改变及其相关因素。方法 应用脉搏波传导速度(PWV)自动测量系统测定颈动脉-股动脉PWV作为反映大动脉扩张性的参数。对118例老年高血压病患者进行了PWV检测,其中男87例,女31例,年龄64-83岁,平均(67.12±10.26)岁。结果 118例老年高血压病患者的研究结果显示PWV随年龄的增大而增加(P<0 001)。多元逐步回归分析结果表明年龄、收缩压与反映大动脉扩张性的PWV关系密切(P<0.001)。结论 老年高血压病导致大动脉扩张性降低,年龄、收缩压与患者大动脉扩张性密切相关。

Objective To explore the change in the distensibilily of large arteries and its mfluencing factors m elderly patients with essential hypertension. Methods Automatic measuring system for pulse wave velocity(PWV) was applied to examine carotid-femoral PWV as an index reflecting distensibihty of large arteries. 118 hypertensive patients aged 64-83(mean age 67. 12± 10.26) years were mcluded in the study. Of them, 87 were melas and 31 were females. Results PWV of 118 hypertensive patients increased with increasmg age ( P< 0.001 ). Multivariate regressive analysis demonstrated that age and systolic blood pressure had the close relationship with PWV(P< 0.001). Conclusion Hypertension of the elderly could cause reduction of distensibihty of large arteries. Age and systolic blood pressure had the close relationship with distensibility of large arteries in elderly patients with essential hypertension.