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外周血髓系细胞过氧化物酶特性及相关疾病 被引量：5

The Characteristic of Myeloperoxidase in Peripheral Blood and Its Related Diseases
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摘要 外周血髓过氧化物酶是髓系细胞的特异性标志,主要存在于中性粒细胞和单核细胞的嗜苯胺蓝颗粒中,近几年其在临床工作中的重要性受到广泛关注。全文对其分子结构、基因结构、生物学功能及与临床疾病的关系作一综述。 Myeloperoxidase in peripheral blood is unique to neutrophils and monocytes, which exists mainly in azurophilic granules. In recent years, it has attracted extensive concern in clinic. The general properties, gene structure, functional aspects and its related diseases are reviewed in this paper.
作者 王永静 陈学良
机构地区 山东大学齐鲁医院
出处 《肿瘤学杂志》 CAS 2004年第6期440-442,共3页 Journal of Chinese Oncology
关键词 髓过氧化物酶 中性粒细胞 致癌物 基因多态性 myeloperoxidase neutrophil carcinogen gene polymorphism
分类号 R730.2 [医药卫生—肿瘤]
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参考文献23

  • 1[1]J Arnhold.Properties,functioned,and secretion of human myeloperoxidase[J].Biochemistry,2004,69:4-9.
  • 2邢宇坤,张伟.中性粒细胞呼吸爆发的产生机制及其炎症效应[J].基础医学与临床,2004,24(1):1-6. 被引量：40
  • 3[3]Bumer U, Furtmuller PG, Kettle AJ, et al. Mechanism of reaction of myeloperoxidase with nitrite[J]. J Biol Chem,2000, 275:20597-20601.
  • 4[4]Rosen H, Crowley JR, Heinecke JW. Human neutrophils use the myeloperoxidase-hydrogen peroxide-chloride system to chlorinate but not nitrate bacterial protein during phagocytosis [J]. J Biol Chem, 2002, 277:30463-30468.
  • 5[5]Foster CB, Lehmbecher T, Mol F, et al. Host defense molecule polymorphisms influence the risk for immunemediated complication in chronic granulomatous diseases[J]. J Clin Investing, 1998, 102:2146-2155.
  • 6[6]Del Santo P, Moneti G, Salvadori M, et al. Levels of the adducts of 4-aminobiphenyl to hemoglobin in control subjects and bladder carcinoma patient[J]. Cancer Lett, 1991,60(3):245-251.
  • 7[7]Huges MF, Smith B J, Eling TE. The oxidation of 4-aminobiphenyl by horseradish peroxidase[J].Chem Res Toxicol,1992, 5(3):340-345.
  • 8林东昕,Kadl.,FF.人白细胞髓过氧化物酶代谢活化致癌物4－氨基联苯[J].中国药理学与毒理学杂志,1994,8(3):221-226. 被引量：4
  • 9[9]Takemura T, Granger DN, Evans DJ Jr, et al. Extract of Helicobacter pylori induces neutrophils to injure endothelial cells and contains antielastase activity[J]. Gastroenterology, 1996, 271:14412-14420.
  • 10[10]Kim JS, Jung HC, Kim JM, et al. Helicobacter pylori watersoluble surface proteins activate human neutrophils and up-regulate expression of CXC chemokines [J]. Dig Dis Sci ,2000, 45:83-92.

二级参考文献39

  • 1[1]Witko-Sarsat V,Rieu P,Descamps-Latscha B,et al.Neutrophils:molecules,functions and pathophysiological aspects[J].Lab Invest,2000,80:617-653.
  • 2[2]Kume A,Dinauer MC.Retrovirus-mediated reconstitution of respiratory burst activity in X-linked chronic granulomatous disease cells[J].Blood,1994,84:3311-3316.
  • 3[3]Babior BM.NADPH oxidase:an update[J].Blood,1999,93:1464-1476.
  • 4[4]Dang PM,Cross AR,Babior BM.Assembly of the neutrophil respiratory burst oxidase:a direct interaction between p67PHOX and cytochrome b558[J].Proc Natl Acad Sci USA,2001,98:3001-3005.
  • 5[5]Bokoch GM,Quilliam LA,Bohl BP,et al.Inhibition of Rap1A binding to cytochrome b558 of NADPH oxidase by phosphorylation of Rap1A[J].Science,1991,254:1794-1796.
  • 6[6]Maly FE,Quilliam LA,Dorseuil O,et al.Activated or dominant inhibitory mutants of Rap1A decrease the oxidative burst of Epstein-Barr virus-transformed human B lymphocytes[J].J Biol Chem,1994,269:18743-18746.
  • 7[7]DeLeo FR,Allen LA,Apicella M,et al.NADPH oxidase activation and assembly during phagocytosis[J].J Immunol,1999,163:6732-6740.
  • 8[8]Kobayashi T,Robinson JM,Seguchi H.Identification of intracellular sites of superoxide production in stimulated neutrophils[J].J Cell Sci,1998,111:81-91.
  • 9[9]Dahlgren C,Karlsson A.Respiratory burst in human neutrophils[J].J Immunol Methods,1999,232:3-14.
  • 10[10]Hampton MB,Kettle AJ,Winterbourn CC.Inside the neutrophil phagosome:oxidants,myeloperoxidase,and bacterial killing[J].Blood,1998,92:3007-3017.

共引文献61

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肿瘤学杂志
2004年 第6期

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