4种慢性乙型肝炎治疗方案的成本-效果分析

Cost-effectiveness analysis of 4 therapeutic schemes for chronic hepatitis B

目的:探讨不同药物治疗方案对同一种疾病所产生的效果。方法:运用药物经济学成本-效果分析方法对4种慢性乙型肝炎治疗方案(A-苦参素注射液、B-拉米夫定+胸腺肽、C-干扰素、D-拉米夫定)进行回顾性分析评价。结果:4种方案的有效率分别为74.14％、91.25％、82.86％、83.33％;不良反应发生率分别为12.07％、8.75％、38.57％、1.39％;成本-效果比分别为88.83、134.89、174.11、91.03。结论:D方案为最佳治疗方案。

Objective:To evaluate the economic effectiveness of different drug therapeutic schemes for the same disease. Methods: Using pharmacoeconomical cost-effectiveness analysis,four therapeutic schemes for chronic hepatitis B ( A-alkoloids sophora injection, B-lamivudine + thymosin, C-interferon, D-lamivudine) were compared. Results: The effective rates of four groups were 74. 14% , 91. 25% ,82. 86% and 83. 33% respectively; The adverse drug reaction rates were 12. 07% ,8. 75% ,38. 57% and 1. 39% . And the cost - effectiveness ratios were respectively 88. 83 ,134. 89,174. 11 and 91. 03. Conclusion:Schemes D are the best one.