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基于硅微通道——毛细血管模型研究烧伤鼠红细胞变形特性 被引量:1

Research on RCD of burned rats based on model of silicon microchannels-capillary
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摘要 目前检验红细胞变形性已广泛作为诊断的辅助手段。本文做了红细胞悬浮液在等压下通过硅微通道的实验,主要测量了烧伤鼠的红细胞变形能力的3个参数:IF、β、ε。实验表明,上述参数可从不同角度反映出细胞流变特性的改变。再结合对流路的观察,还可以对细胞流变特性做出较全面和准确的评价。 The red cell deformability (RCD) has been taken as a diagnostic aid in recent years. The dilute red cell suspension passes through the silicon microch annels under constant suction pressure. Such three parameters of RCD are measure d as IF (filtration index), and The results show that the above-mentioned parameters can reflect the changes of cell rheological characteristics from dif ferent aspects. With the observation of the flow passage, the rehological charac teristics can be evaluated accurately and comprehensively.
出处 《医疗卫生装备》 CAS 2004年第12期11-12,共2页 Chinese Medical Equipment Journal
基金 国家自然科学基金资助
关键词 红细胞变形性 硅微通道 烧伤 悬浮液 RCD silicon microchannel burn suspension
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  • 1郑小林,吴楠,卢晓,蔡绍皙,吴云鹏,彭承琳,何林,胡刚毅,郑娥,崔茂镜.一种新的硅微通道红细胞变形性测量方法[J].中国生物医学工程学报,2000,19(1):7-12. 被引量:10
  • 2Yuji Kikuchi,Kazuo Sato,Yoshinori Mizugushi. Modified Cell-Flow Microchannels in Single-Crystal Silicon Substrate and Flow Behav ior of BloodCells. Microvascular Research,1994,47:222
  • 3Yuji Kikuchi. Effect of Leukocytes and Platelets on Blood Flow througe a Paralle Array of Microchannels. Microvascular Research,1995,50:288
  • 4Sutton N,Tracey MC,Johnston ID,et al.A Noval Instrument for Studying the Flow Behavior of Erythrocytes through Microchannels Simulating Human Blood Capillaries. Microvascular Research, 1997,53:272
  • 5严宗毅.介绍细胞过孔分析仪[J].中国血液流变学杂志,1998,8(1):26-32. 被引量:3

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