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大肠癌组织中MMP-2、MMP-7的基因表达 被引量:4

The expressions of MMP-2 and MMP-7 in colorectal cancer
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摘要 目的 :观察MMP 2和MMP 7在大肠癌组织与正常组织中表达的差异。方法 :取 2 8例大肠癌组织及肿瘤周围正常组织 ,用RT PCR方法检测肿瘤组织及正常组织中MMP 2和MMP 7的表达。结果 :MMP 2和MMP 7在大肠癌组织中的表达率和表达水平高于周围的正常组织 (P <0 0 5 )。结论 :MMP 2和MMP Objective: To investigate the expressions of MMP-2 and MMP-7 between colorectal cancer and normal tissue.Methods: RT-PCR was used to determine the expressions of MMP-2 and MMP-7 in colorectal cancer and normal tissue.Results: The expression rate and level of MMP-2 and MMP-7 were higher in cancerous tissue than that in normal tissue(P<0.05).Conclusion:MMP-2 and MMP-7 may play an important role in the progression of colorectal cancer.
出处 《中国现代普通外科进展》 CAS 2004年第6期358-359,共2页 Chinese Journal of Current Advances in General Surgery
基金 山东省卫生厅科研基金资助项目 (HZ0 75 )
关键词 结直肠肿瘤 明胶酶A 基质溶解因子 Colorectal neoplasms·Gelatinase A·Matrilysin
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