环磷酸腺苷葡胺对急性心肌梗死患者QT离散度的影响

EFFECTS OF MEGLUMINE CYCLIC ADENYLATE ON QT DISPERSION OF PATIENTS WITH ACUTE MYOCARDIAL INFARCTION

目的 :探讨环磷酸腺苷葡胺对急性心肌梗死患者 QT离散度的影响。方法 :将急性心肌梗死患者随机分为试验组和对照组 ,分别给予环磷酸腺苷葡胺和安慰剂 ,测定患者用药前后 QT离散度。结果 :试验组的 QT离散度比对照组显著降低 (P <0 .0 1 )。结论 :环磷酸腺苷葡胺可降低急性心肌梗死患者

Objective:To investigate the clinical effects of meglumine cyclic adenylate(MCA) on QT dispersion of patients with acute myocardial infarction (AMI).Methods:60 patients with AMI were randonmized into two groups:experiment group and control group. Both groups of patients were treated with the same ordinary methods, but MCA was administered in the experiment group. The period of treatment was 14 days. QT dispersion of every case was measured before and after MCA administration. Result:QT dispersion of the experiment group was significiently lower than that of the control group(P<0 01).Conclusion:MCA can be used to reduce QT dispersion of patients with AMI.