摘要
目的与方法:应用聚合酶链反应(PCR)技术对56例肺癌石蜡包埋标本进行C-myc基因的研究.结果:C-myc基因扩增与组织学类型、临床病理分期及淋巴结转移有密切关系(P<0.05),C-myc基因扩增者,分化程度较低,临床病理分期较晚,淋巴结转移多.同时还发现C-myc基因扩增与预后有明显关系(P<0.05),C-myc基因扩增者预后较差.结论:提示C-myc基因可以作为判断肺癌预后的检测指标之一.
Purpose and Methods:Using polymerase chain reaction, we analysed 56 samples of lung cancerat molecular level. Results:C-myc oncogene ampliication was found to be related to histological types, TNM staging, lymph node metastasis and also prognosis (p<0. 05).Conclusion:C-myc oncogene may be the prognostic factor for the patients with lung cancer.
出处
《临床肿瘤学杂志》
CAS
1998年第1期17-18,共2页
Chinese Clinical Oncology
