人工肝支持系统治疗慢性乙型重型肝炎的疗效观察

Clinical observation of therapeutic effect with artificial liver support system in chronic severe hepatitis B

[目的 ]观察人工肝支持系统治疗慢性乙型重型肝炎的疗效。 [方法 ]177名患者分成治疗组和对照组 ,治疗组在综合药物治疗的基础上加用人工肝支持系统 ,而对照组只采用药物治疗。观察2组患者临床症状、肝功能、凝血酶原时间 (PT)、凝血酶原活动度 (PTA)及各期存活率。 [结果 ]治疗组在临床症状、肝功能、PT、PTA等指标的改善上明显优于对照组 (P >0 .0 5 ) ;治疗组早、中期存活率明显优于对照组 (P >0 .0 5 )。 [结论 ]联合人工肝支持系统能明显提高药物治疗慢性乙型重型肝炎的疗效。

[Objective] To observe the therapeutic effect of patients with chronic severe hepatitis B after using artificial liver support system (ALSS). [Methods] Of 177 patients were divided into 2 groups. The treatment group was used by ALSS in addition to the basic treatment, while the control group was used only by the basic treatment. Then observe the patients' clinical symptom,liver function, PT, PTA and survival rate. [Results] The treatment group was superior to the control group in all of the indexes that mentioned(P>0.05).The survival rate of the treatment group was superior to the control group in early or middle stage (P>0.05).[Conclusion] It can improve the therapeutic effect assisted by ALSS in chronic severe hepatitis B.