社区居民血糖水平及其变异性与血压的关系

Relationship between blood glucose level, glucose fluctuations and blood pressure among permanent inhabitant

目的 :探讨自然人群血糖水平与血压水平之间的相互关系。方法 :测量 182 8名社区居民血压 ,并进行口服 75 g葡萄糖耐量试验。结果 :高血压比率为 38.5 %。高血压人群空腹血糖、糖负荷 2 h血糖和血糖变异系数显著高于正常血压人群 ,即使是在糖耐量正常人群 ,血压仍在高于中位数血糖组显著升高。血压水平随糖代谢异常而显著升高。结论 :自然人群中血压水平与血糖水平存在密切的内在关系。

Objective: To evaluate the association of blood glucose level, glucose fluctuation with blood pressure level in permanent inhabitant. Methods: Blood pressure level was measured and oral 75 gram glucose tolerance test was performed to measure fasting and 2 hours after glucose load blood glucose level in 1828 inhabitants. Results: The ratio of hypertension according to 1999 WHO criteria was 38.5%. There were significant increase in fasting and 2 hours after glucose load blood glucose level,glucose fluctuations in subjects with hypertension compared with those without hypertension. Significant enhancement of blood pressure level was observed even in inhabitants with normal glucose tolerance with blood glucose level over median. Blood pressure levels were significantly increased with the change in the metabolic control from NGT to DM. There were significant positive correlations between blood pressure levels and fasting, 2 hours after glucose load blood glucose levels. Conclusions: There is close relationship between blood pressure level and blood glucose level in inhabitants.