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磷酸钙生物陶瓷的孔性、内部连通性及表面形态对骨质再生的影响 被引量：1

Role of pores,interconnections,and their surface topographies in porous calcium phosphate bioceramics on bone recolonization
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摘要 磷酸钙生物陶瓷是一类具有良好生物相容性和骨传导性的生物活性材料,由于其成分与骨的无机组分基本相当,是目前公认的最具前途的硬组织修复材料,将该材料制成多孔结构,更有利于新生骨组织生长所需的物质交流,促进新生骨形成,因而成为近年来生物材料的研究热点之一。本文从多孔磷酸钙生物陶瓷与组织的响应关系角度出发,评述了近年来磷酸钙生物陶瓷的孔性、孔和孔间的内部连通性及孔的表面形态对骨质再生影响的研究进展。 Calcium phosphate bioceramics have remarkable biocompatibility and osteoconductivity.Their mineral composition is very close to that of normal bone.The porous structure of calcium phosphate biomaterials favors cellular and vascular penetration,which assures bone ingrowth,thus,the applications of porous calcium phosphate bioceramics as bone substitute have received considerable attention.On the relationship between the porous structure and new bone formation,the recent development was reviewed in this paper.[
作者 季金苟 傅小妮 万昌秀 苟立
机构地区 四川大学无机非金属材料系 四川大学医用高分子与人工器官系
出处 《国外医学（生物医学工程分册）》 CAS 2004年第6期364-368,共5页 Foreign Medical Sciences(Biomedical Engineering Fascicle)
基金 国家重大基础研究资助项目(973G1999064701)
关键词 磷酸钙生物陶瓷 孔性 内部连通性 表面形态 骨质再生 calcium phosphate bioceramics pore interconnection surface topography bone recolonization
分类号 R318.08 [医药卫生—生物医学工程]
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参考文献24

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同被引文献14

  • 1郭大刚,孙浩亮,赵晓云,徐可为,憨勇.磷酸四钙的高温固相合成及冷却速率对其纯度的影响[J].硅酸盐学报,2004,32(6):689-693. 被引量：5
  • 2赵晓云,郭大刚,憨勇,徐可为.含锶磷酸钙骨水泥的制备及性能研究[J].无机材料学报,2005,20(5):1167-1173. 被引量：10
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  • 6LU J X,FLAUTRE B,ANSELME K,et al.Role of interconnections in porous bioceramics on bone recolonization in vitro and in vivo[J].Mater Sci:Mater Med,1999,10(1):111 -120.
  • 7FUJIBAYASHI S,NEO M,KIM H M,etal.Osteoconduction of porous bioactive titanium metal[J].Biomaterials,2004,25(3):443-450.
  • 8HABIBOVIE P,YUAN Huipin,van der VALK C M,et al.3D microenvironment as essential element for osteoinduction by biomaterials[J].Biomaterials,2005,26 (17):3 565-3 575.
  • 9YUAN Huipin,YANG Zongjian,LI Yubao,et al.Osteoinduction by calcium phosphate biomaterials[J].Mater Sci:Mater Med,1998,9(2):723-726.
  • 10RIBEIRO A S,MALAFAVA P B,REIS R L.Two new routes for producing porous bioactive ceramics:polyurethane precursors and microwave baking[J].Bioceramics,2001,11(3):735-738.

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国外医学（生物医学工程分册）
2004年 第6期

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