四种抑制剂对人白细胞脂加氧酶的抑制作用

INHIBITION OF FOUR INHIBITORS ON LIPOXYGENASE ACTIVITY OF HUMAN LEUCOCYTES

用无色孔雀绿的方法测定了几种抑制剂对人白细胞脂加氧酶的抑制作用。其中,消炎痛对脂加氧酶无抑制作用,NDGA、槲皮素、黄芩甙的 IC_(50)分别为1.8μmol/L,2.86 μmol/L 和1.8

The inhibition of some inhibitors on lipoxygenase activity of human leucocytes was assayed using leuco—malachite green method.The inhibition of indomethacin on lipoxygenase was not found.The IC_(50) for nordihydrognaioretic acid,quercetin and baicalin was found to be 1.8μmol/ L,2.86μmol/L and 1.8μg/ml,respectively.