摘要
从SD大鼠头颅部骨膜组织中培养分离出的骨原细胞,是体外研究骨组织构成、代谢的极好材料。骨原细胞在形态上与成纤维细胞相似。本实验结果表明:25-羟维生素D_3及雌二醇、睾丸酮类性激素促进体外培养骨原细胞的增殖;孕激素对骨原细胞的生长没有明显的影响。
We isolated and established osteoblastic cells derived from rat periosteum in culture. Their growth depended on the presence of ascorbic acid and α-glycerophoshate-Na_2.Vitamin D_3.Estra- diol and testosterone can increase the proliferation of osteoblastic cells.
关键词
骨原细胞
雌二醇
碱性磷酸酶
osteoblastic cell
vitamin D_3
estradiol
testosterone