21例人血过氧化脂质检测分析

Analysis of Lipid Peroxide Objection(LPO) Measured in Human Plasma

对21例风湿性心脏病(RHD)患者及30例健康者进行人血过氧化脂质(LPO)水平检测,结果发现:RHD患者血LPO水平明显高于正常组,且多瓣模病变者血LPO水平高于单瓣膜病变者;在风湿活动期血LPO水平增高更加明显,治疗后则显著下降。表明脂质过氧化增加在RHD的发生、发展中可能起重要的促进作用。

We have measured the level Chang Zhou of plasma LPO of twenty-one pa- tients with rheumatic heart disease (RHD) and that in thirty normal subjects. The results showed that the level of LPO in RHD patient group was much higher than that in the normal group; the level of LPO in the polyvalvular lesions group was higher than that in the mono- valvular lesions group. During the rheumatic attack, LPO level was much higher whereas it play reduced remarkably after the treatment. It suggests that increased lipid peroxidation might play an important part in occurrence and development of RHD.