肝豆状核变性的磁共振影像学所见及其形成机理

Magnetic Resonance Imaging and Its Pathogenesis of Hepatolenticular Degeneration

肝豆状核变性的磁共振影像学所见及其形成机理刘吉良，张凤芝，李义召，张守瑞，韩丹春，刘少河（山东聊城地区东昌医院神经科，聊城２５２０００）肝豆状核变性（ＨＬＤ），是以遗传性铜代谢障碍所致的肝硬变和以基底节为主的脑部变性为特征的疾病。ＨＬＤ的磁共振影像（...

Abstract The relationship among MRI manifestations, clinical symptoms and therapeutic effects of hepatolenticular degeneration(HLD) was studied in l2 cases with HLD. The results showed that the most commonly pathological sites of HLD were nucleus caudatus,putamen, thalamus,usually bilateral.The foci of MRI imaging were essentially compatible with the clinical symptoms,Some patients might have clinical symptoms, but normal MRI findings.Sometimes MRI could detect the HLD patients without clinical symptoms. The pathogenesis of findings of HLD was discussed.