补阳还五汤治疗早期缺血性中风SOD、MDA变化的研究

Study on SOD and MDA changes in Patients with Early Stage IschemicApoplexy treated with Buyang Huanwu Decoction (补阳还五汤)

用补阳还五汤治疗早期缺血性中风患者６０例，进行了治疗前后ＳＯＤ、ＭＤＡ的测定，并与６５例健康人进行了对比分析。结果发现早期缺血性中风患者治疗前ＳＯＤ显著低于对照组、而ＭＤＡ则明显高于对照组；经用补阳还五汤治疗后ＳＯＤ显著升高，ＭＤＡ显著降低，而与对照组相比则无显著性差异，说明补阳还五汤可通过提高机体清除自由基能力、降低脂质过氧化损伤而达到治疗早期缺血性中风之目的。补阳还五汤；早期缺血性中风；超氧化物歧化酶；

OD and MDA in serum were determined in 60 patients with early stase ischemic apoplexy before and after beingtreated with Buyang Huanwu Decoction, and compared with those in 65 healthy People, The results showed that SODwas significantly lower and MDA was obviously higher in patients than those in controls (p<0. 01 ) before being treated, and both of them took obviously changes in patients after being treated. (P>0.01 ), and no differense was observed between patients and controls (P<0. 05). Our studies revealed that patients' power of cleaning free radical decreased and lipid peroxidation increases. and it is by cleaning free radical and weakening lipid peroxidation thatBuyang Huanwu Decoction could treat Early Stage Ischemic Apoplexy.