38例男性泌尿生殖道支原体感染与药物敏感性分析

Analysis of Mycoplasma Infection and Drug Sensitivity in Urethristis (Report of 38 Male Cases)

目的 :观察男性尿道炎患者解脲支原体 (Uu)和人型支原体 (Mh)的阳性率、药敏试验 ,为临床用药提供借鉴。方法 :从我中心性病门诊男性尿道炎患者中选择 38例仅有支原体感染的患者 ,取前列腺液和尿道拭子培养支原体 ,观察支原体类型 ,并做体外药物敏感性分析。结果 :38例支原体感染菌株中解脲支原体 (Uu)阳性 33例 (86 8% )。人型支原体 (Mh)阳性 2例 (5 3% )、解脲支原体 (Uu)和人型支原体 (Mh)混合感染阳性 3例 (7 9% )。药敏试验中敏感性最高的是克拉霉素、阿齐霉素、罗红霉素、司帕沙星 ;强力霉素、美满霉素次之 ;敏感性最差的是交沙霉素、壮观霉素。结论 :男性泌尿道支原体感染以解脲支原体 (Uu)为主 ,体外药物敏感性分析 ,敏感性最高的是克拉霉素、阿齐霉素、罗红霉素、司帕沙星 ;强力霉素、美满霉素次之 ;交沙霉素、壮观霉素最差 ,临床上合理选用敏感抗生素 ,进行规范治疗 。

Objective:To investigate the positive rate of Ureaplasma urealyticum (Uu) mycoplasma hominis (Mh) and experiment of drug sensitivity,for providing evidence for clinical pharmaceutical treatment.Methods:Samples of urethal and prostatic secretions were taken form 38 patients with urethristis infected by single mycoplasma.The types of mycoplasma were observed.Drug sensitivities in vitro were analyzed.Result:The infected strain was Uu in 33 of 38 cases (86.8%),Mh in 2 of 38 cases (5.3%),Combined infection in 3 of 38 cases (7.9%).The Drug sensitivities of CLA,AzI,ROX and SPA were highest;that of Dox,Min were higher and that of Jas and SPE were the lowest.Conclusion:Uu is the main pathogen in male urethristis infected by mycoplasma.Proper sensitive antibiotics and standard therapy can control infection effectively.