摘要
对12例大肠癌手术切除标本的癌组织、癌旁组织及远癌组织作 GGT 生物化学研究.结果显示 GGT 活力在癌组织>癌旁组织>远癌组织,前二者与后者之间差异有显著性(P<0.05).表明,GGT 在癌旁组织的异常表达早于形态学癌变之前,GGT 可望成为大肠癌癌前期病变及早期癌的生化标志物.
Gamma glutamyl transpeptidase(GGT)in cancer tissue,the tissue adjacent to cancer and the tissue remote to cancer from twelve cases of large bowel carcinoma during operation was studied.Clinical research showed that GGT activity was higher in carcinoma than in the tissue adjacent to cancer,and higher in tissue adjacent to cancer than in the tissue remote to cancer.Significant difference in GGT activity was demonstrated between the first two kinds of tissues and the third kind.Research showed that abnormal expression of GGT in the tissue adjacent to cancer was prior to anatomy becoming cancer.GGT might be biochemical mark- er for precancerous lesions of large bowel carcinoma and early cancer.
出处
《南通医学院学报》
1993年第2期121-122,共2页
ACTA Academiae Medicinae Nantong
关键词
大肠肿瘤
谷氨酰转肽酶
肿瘤标志物
large bowel carcinoma
gamma glutamyl transpeptidase
tumor marker