摘要
本文报告应用光镜和电镜对20例精素静脉曲张不育症患者的睾丸和附睾组织进行了病理改变和超微结构的观察。生精细胞脱落、间质小血管病变和对侧睾丸病理损害是精素静脉曲张不育症睾丸的三种主要病理变化,其中间质小血管病变更具有特征性。电镜发现精原细胞存在着明显的病理变化,因此精索静脉曲张不育症患者精子生成障碍涉及到精原细胞的增殖,精母细胞的成熟分裂及细胞变态三个过程。病检表明附睾有一定损害,具有重要病理生理意义,认为是精索静脉曲张导致不育的重要因素。
A study of pathological changes and ultrastructural observation of testes and epididymis taken from 20 infertile men with varicocele was performed.
The three main pathological changes were exfoliation of germ cells, impairment of interstitial tissue and pathological alterations occurred in the contralateral testis, among which the interstitial small blood vessels might be the most characteristic lesion. Distinct changes were revealed in the spermatogonia by electron microscopy.
Epididymal impairment in some cases was observed by epididymal biopsies. The possible pathophysiological significance of these change was discussed.
关键词
精索静脉曲张
不育症
睾丸
附睾
病理
Varicocele
Infertility
Testes
Epididymis
Pathological
Changes
