生育与不育男性精浆的转铁蛋白

TRANSFERRIN LEVELES IN SEMINAL PLASMA OF FERTILE AND INFERTILE MEN

147例不育男性的精浆转铁蛋白(Tf)的平均含量(20.1±0.89g/ml(显著地低于115例正常生育男性的Tf的平均含量(28.2±0.7μg/ml,p<0.01)。其中无精症组、严重少精症组,中度少精症组和仅精子密度正常组的精浆Tf含量(分别为15.8±0.9,18.5±0.2,19.0±1.6和22.4±1.6μg/ml)与正常生育组比较均有显著差异(P<0.01)。血清FSH水平升高组精浆Tf含量显著低于血FSH水平正常组。本研究结果表明精浆Tf可能是反映睾丸支持细胞功能的有意义的指标。

Seminal plasmal transferrin (T_f) concentration of 147 infertile patients (20.1±0.8μg/ml) were significantly lower than 115 proven fertile donors (28.2 ±0.7μg/ml P<0.01). The seminal T_f concentration of patients with azoospermia, severe oligozoospermia, moderate oligozoospermia and normal sperm density only (15.8±0.9、 18.4±2.0, 19.0±1.6, and 22.4±1.6μg/ml, respectively) were all significant different to fertile donors (P<0.01).The seminal T_f levels of the high FSH gronp were significantly lower than normal FSH group. It suggested that the seminal T_f could be considered as an useful marker of Sertoli cell function.