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具有全能干细胞特征的成年祖细胞—MAPCs

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摘要 阐述近年发现一种具有胚胎干细胞样特征的多能成年祖细胞(multipotent adult progenitor cells,MAPCs)的研究进展。MAPCs 在体外不仅可以分化为外胚层、内胚层、中胚层细胞,而且诱导分化的血管内皮细胞和肝细胞都具有功能性特征;MAPCs 强大的分化潜能和扩增能力,为遗传性和退行性等疾病进行细胞治疗提供合适的细胞来源,MAPCs 在组织工程学和临床治疗中有着良好的应用前景。
作者 袁雅生 迟放鲁
机构地区 复旦大学附属眼鼻喉科医院耳神经颅底外科
出处 《中国眼耳鼻喉科杂志》 2004年第6期403-405,共3页 Chinese Journal of Ophthalmology and Otorhinolaryngology
基金 国家自然基金资助项目(30371522)
关键词 成年祖细胞 MAPCs 生物学特性 胚胎干细胞 细胞增殖
分类号 R329 [医药卫生—人体解剖和组织胚胎学]
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参考文献15

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二级参考文献10

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中国眼耳鼻喉科杂志
2004年 第6期

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