传染性非典型肺炎并急性呼吸窘迫综合征的治疗

Treatment of severe acute respiratory syndrome with acute respiratory distress syndrome

目的探讨传染性非典型肺炎(世界卫生组织又称严重急性呼吸综合征,SARS)并急性呼吸窘迫综合征(ARDS)的治疗。方法以2002年12月至2003年3月,我院及广州医学院第一附院临床诊断SARS并ARDS的12例患者为对象,回顾性分析呼吸机通气模式、糖皮质激素、深度镇静等方面的应用。结果压力控制模式(PCV)优于同步间歇指令通气(SIMV)和持续气道正压通气(CPAP)及双相气道正压通气(BIPAP),早期规律使用糖皮质激素可减少死亡率,深度镇静可减少气胸出现。结论PCV模式通气,早期规律使用糖皮质激素,深度镇静治疗SARS并ARDS疗效良好。

Objective To investigate the management of severe acute respiratory syndrome (SARS) with acute respiratory distress syndrome (ARDS). Methods The clinical data of 12 patients with SARS were studied retrospectively. Results Pressure control ventilation(PCV) mode was superior to synchronized intermitten mandatory ventilation(SIMV), continuous positive airway pressure (CPAP) or biphasic positive airway pressure(BIPAP). The use of corticosteriod early and regularly could reduce the mortality. Deep sedation would reduce the occurrence of pneumothorax. Conclusion The treatment of PCV mode, corticosteriod and deep sedation is very effective to SARS with ARDS.