硬膜外吗啡术后镇痛更优模式的探讨

Excellent model of analgesia with morphine in epidural space after surgery

目的 观察比较硬膜外不同浓度布比卡因、氟哌利多、新斯的明和小剂量吗啡协同用药以减少吗啡传统用药引起的副作用。方法 80例患者随机分成 4组并使用不同剂量吗啡和不同浓度布比卡因进行对比观察。结果 协同用药各组副作用发生率远较吗啡传统用药低 ,差异有显著性 ;0 .2 %布比卡因协同组与 0 .375 %布比卡因协同组镇痛与副作用相似 ,组间比较差异无显著性。结论 低浓度 (0 .2 % )布比卡因与氟哌利多、新斯的明协同小剂量吗啡 (1.0mg)用于术后镇痛为更优良的方法。

Objective To compare the effects in different concentratio n of bu pivacaine, droperidol and neostigmine with the synergistic use of small dose of morphine. So as to reduce the side effect of the routine use of morphine.Method Eighty patients were divided into four groups randomly and the effects of different dose of morphine and different concentration of bupivacain e were compared.Results The side-effect in synergistic use group was significantly lower than that of morphine routine use group. The effect of analgesia and side effect in synergistic use of 0.2% bupivacaine group was same as synergistic use of 0.375% bupivacaine group. There was no significant differenc e between them. Conclusion Low concentration bupivacaine,droper id ol and neostigmine synergistic use of small dose of morphine is the excellent mo del of analgesia after surgery.