摘要
探讨了用高效液相色谱法测定间苯二甲酸双羟乙酯5磺酸钠(SIPE)的酯交换率的测试条件。采用ZorbaxSBC18色谱柱,测试波长为230nm,以甲醇/水(21∶79)为流动相,流速为1.0mL/min,能快速、准确地测定SIPE的酯交换率。该法可用于SIPE的检测和质量控制。
A method for determining the ester exchanging rate in the synthesis of 5-sodium sulfo bis( Hydroxyethyl) isophthalate by high performance liquid chromatography ( HPLC) was developed. It was carried out on a Zorbax SB-C-18 column with diolde array detector at 230 nm, using methanol/water(21:79) as mobile phase at a flow rate of 1.0 mL/min. This method is specific, rapid and accurate.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
2004年第12期1653-1655,共3页
Chinese Journal of Analytical Chemistry
