哮喘患者血清TNF-α和G-CSF的检测分析
Analysis of Tumor Necrosis Factor- alpha and Granulocyte-Macrophagecolony-stimulating Factor in Serum in Patients with Asthma
摘要
目的:探讨哮喘患者血清肿瘤坏死因子α(TNF-α)和粒细胞集落刺激因子(G-CSF)的变化.方法:采用双抗体夹心ELISA法检测患者血清TNF-α和G-CSF水平.结果:哮喘患者血清TNF-α和G-CSF明显高于健康对照组(P＜0.01),其中合并肺炎组最高;治疗后血清TNF-α和G-CSF明显下降(P＜0.01);血清TNF-α与G-CSF 呈正相关(r=0.842,P＜0.01).结论:哮喘患者血清TNF-α和G-CSF升高,二者参与哮喘病理炎症发展;检测TNF-α和G-CSF对临床治疗有一定指导意义.
出处
《医学理论与实践》
2004年第12期1389-1390,共2页
The Journal of Medical Theory and Practice
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