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用ENU诱导斑马鱼突变的初步研究 被引量:4

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摘要 斑马鱼作为一种脊椎动物发育模型,正越来越受到重视.用ENU诱变的方法,建立了320个斑马鱼F2家系.通过对F3代胚胎的表型观察,鉴定在外包、体轴、体节、头部、心血管系统等表现异常的突变体.目前已获得35个突变品系,其中以体轴和体节异常的突变体为主.这些突变体斑马鱼品系的建立为克隆突变的基因、研究胚胎早期发育机制打下了良好的基础.
出处 《科学通报》 EI CAS CSCD 北大核心 2004年第20期2078-2082,共5页 Chinese Science Bulletin
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