重度有机磷中毒患者阿托品化观察指标的探讨

Indexes for Atropinization in Treatment of Severe Poisoning by Organophosphorus Pesticides

目的：探讨重度有机磷中毒患者阿托品化的观察指标。方法：在救治145例重度有机磷农药中毒患者中，对常用的阿托品化指标及股动脉抢击音、体温等7项指标进行观察。结果：瞳孔散大和肺部湿罗青显著减少两项指标在阿托品化前后无显著差异（P＞0．05），而其他指标则差异非常显著（P＜0．01）、结论：瞳孔散大和肺部湿罗音显著减少仅可作为辅助观察指标或应用阿托品后有效的一般指证，而体温升高在37．5～38．8℃和股动脉枪击直对阿托品化的判断价值大。轻度躁动不安是判断阿托品化比较可靠的指标。

Objectives: To evaluate the indexes for atropinization in the treatment of severe poisoning byorganophosphorus pesticides. Methods: Svvn indexes for atropinization were observed and evaluated in thetreatment of 145 cases of severe poisoning by organophosphorus pesticides poisoning. Results: showed that in-dexes for platycoria and reduction of pulmonary wet rale were not significantly changed before and after at-ropinization (P> 0. 05 ), but other five indexes had significant difference statistically (P< 0. 01). Conclusions:Body temperature ranges from 37. 5 to 38. 8 ℃. Pistol-shot sound and slight restlessness may be valuable in-dexes for the evaluation of atropinization. However, Platycoria and reduction of pulmonary wet rale may also behelpful for the diagnosis of atropinization.