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转运结构域的研究进展 被引量：2

Advances in Translocation Domain
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摘要 利用非病毒载体转运目的基因时 ,具有转运结构域的蛋白质或多肽片段可以有效地促进外源效应分子进入细胞浆 ,发挥其效应。这些转运结构域广泛的存在于毒素蛋白、病毒蛋白、转录因子、同源结构域及合成肽当中。 Proteins or peptides containing translocation domain can efficiently improve the delivery of therapeutic molecules into cells when using nonviral vectors to deliver genes. These translocation domains exist in bacterial toxin, viral proteins, transcriptional factors, homodomain and synthetic peptides.
作者 张莉 赵晶 杨安钢 王成济
机构地区 第四军医大学基础部生物化学与分子生物学教研室
出处 《医学分子生物学杂志》 CAS CSCD 2004年第6期351-354,共4页 Journal of Medical Molecular Biology
基金 国家自然科学基金 (No . 3 0 3 70 3 14 ) 全军医药卫生科研基金重点项目 (No .0 1Z0 90 )
关键词 转运结构域 非病毒基因转移 转运 translocation domain nonviral gene transfer translocation
分类号 Q78 [生物学—分子生物学]
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参考文献22

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同被引文献39

  • 1王海娟,林晨,詹启敏.PUMA的研究进展[J].国外医学（遗传学分册）,2004,27(6):338-340. 被引量：6
  • 2郝延璋,张林杰.Puma/Bbc3在细胞凋亡中的作用及其机制[J].医学分子生物学杂志,2004,1(6):366-369. 被引量：1
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医学分子生物学杂志
2004年 第6期

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