摘要
目的通过重组乙肝疫苗联合干扰素抗HBV研究,探讨其治疗乙型肝炎的可行性及作用机制。方法两组慢性乙型肝炎患者均常规给予保肝降酶药物,联合组每周3次肌注IFNα2b3MU,另加重组乙肝疫苗20μg每月1次三角肌处肌注,疗程为6个月。对照组只单独肌注IFNα2b,分别观察其抗HBV及改善肝功能情况。结果联合组抗HBV及改善肝功能效果与对照组比较有显著差异。结论重组乙肝疫苗联合干扰素抗HBV显示出良好的治疗前景。
Objective:Through the anti-HBV treatment of recombinant HBV vaccine combined Interferon,investigate its therapeutic effect and its mechanism.Methods:Both two groups of patients with chronic hepatitis B were given routine hepatoprotective treatment,the combing group was injected Interferon α-2b 3MU three times every week and the recombinant HBV vaccine 20μg once every month in deltoid. The control group was only injected with Interferon α-2b.To estimate the two groups liver function and anti-HBV effect. Results: The degree of improving liver function in combing group was superior to the control group, the difference between the two groups was obvious. Conclusion: The treatment of recombinant HBV vaccine combined Intex feron has evident liver protection.
出处
《中西医结合肝病杂志》
CAS
2004年第6期332-333,共2页
Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases
基金
青岛市科委基金资助课题(NO200499)
