摘要
[目的 ]探讨电针调整胃动力与血管活性肠肽 (VIP)的内在联系。 [方法 ]采用浆膜法测定胃电数据 ,放射和免疫组化方法观察针刺足三里穴对束缚冷应激致胃动力紊乱大鼠VIP表达的影响。 [结果 ]与正常组比较 ,束缚冷应激大鼠胃运动频率和波幅升高 (P <0 .0 1) ;与模型组比较 ,电针足三里穴可降低胃运动频率和波幅 (P <0 .0 1) ,同时可影响VIP的表达 (P <0 .0 5 ,<0 .0 1)。 [结论 ]VIP参与了电针对胃动力的调整作用。
Objective] To explore the relationship between vasoactive intestinal peptide(VIP) and modulation of electric acupuncture(EA) on gastric motility. [Methods] Gastric myoelectric activity was measured by serosamethod. The expression of VIP was tested by radioimmunoassay and avidin biotin peroxidase complex. [Results] In rats with gastric motility disorder induced by cold restraining stress, the frequency and amplitude of gastric motility were higher than those in control group( P <0.01).After EA of “Zusanli”(ST36), the frequency and amplitude of gastric motility lowered( P <0.01), while the expression of VIP raised significantly( P <0.05,<0.01) in comparison with those of model group. [Conclusion] VIP is involved in the modulation effect of EA on gastric motility.
出处
《中国中西医结合消化杂志》
CAS
2004年第6期329-331,共3页
Chinese Journal of Integrated Traditional and Western Medicine on Digestion
基金
安徽省高校青年科研基金资助项目 (No .2 0 0 2jq14 3 )
关键词
胃动力紊乱
血管活性肠肽
电针
gastric motility disorder
vasoactive intestinal peptide
electric acupuncture
