电视腹腔镜在辅助生育技术中的应用

Application of laparoscopy in assisted reproduction techniques

目的 探讨电视腹腔镜下输卵管配子移植术 (gameteintrafallopiantransfer,GIFT)的临床应用价值。 方法 采用促性腺激素促超排卵 ,上游法处理精液 ,电视腹腔镜下穿刺取卵 ,输卵管插管移植配子。 结果 19例中妊娠 4例 ,妊娠率2 1 1% ( 4 / 19) ,3例足月分娩 ,1例妊娠流产 ,无严重并发症。 15例未孕者中术后 6月内自然妊娠 5例 ,周期妊娠率 5 6 % ( 5 /89)。 结论 电视腹腔镜下GIFT是一种获得较高妊娠率的辅助生育技术 ,同时治疗了导致不孕的其它盆腔疾患 。

Objective To investigate the clinical significance of gamete intrafallopian transfer (GIFT) under laparoscope. Methods The gonadotropin was adopted to induce superovulation and the spermatic fluid was managed with the swim-up method. After oviums were dislodged by puncture under laparoscope, gametes were transplanted by intubating the fallopian tube. Results Among a total of 19 patients, 4 were pregnant, the pregnancy rate being 21.1% (4/19). Three women had a delivery at term and 1 had an abortion. No serious complications were seen. Of the 15 unfertilized patients, normal pregnancy was observed within 6 months after surgery in 5 patients, the circle pregnancy rate being 5.6% (5/89). Conclusions GIFT under laparoscope is a practical assisted reproductive technique (ART) that may achieve a relatively high pregnancy rate. Some other pelvic diseases resulting in infertility can be treated simultaneously, which contributes to natural fertilization in the future.