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HPV树突状细胞疫苗研究进展 被引量：3

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摘要 人乳头瘤病毒 (HPV)感染在人群中非常普遍 ,尚无有效预防和治疗办法。本文概述了以树突状细胞 (DC)为基础的HPV疫苗研究现状 ,包括病毒蛋白及肽段负载的DC疫苗、HPVˉDNA、RNA、病毒样颗粒刺激的DC疫苗及肿瘤细胞与DC融合疫苗等 ,并讨论了其在尖锐湿疣防治中的可能应用。
作者 王飞 毕志刚
机构地区 南京医科大学第一临床医学院皮肤科
出处 《国外医学（病毒学分册）》 2004年第6期183-187,共5页 Foreign Medical Sciences(Section of Virology)
关键词 HPV-DNA 树突状细胞疫苗 DC疫苗 预防和治疗 HPV疫苗 白及 研究进展 RNA 中非 人群
分类号 R392 [医药卫生—免疫学]
  • 相关文献

参考文献24

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  • 3Rudolf MP, Fausch SC,Da Silva DM, et al. Human dendritic cells are actived by chemicic human papillomavirus type-16 virus like particles and induce epitope-specifichumanT cell responses in virto.J Immunology, 2001,166(10): 5917-5924.
  • 4Thomburg C, Boczkowski D, Gilboa E,et al. Induction of cytotoxic T lymphocytes with dendritic cells transfected with human papillomavirus E6 and E7 RNA: implications for cervical cancer immunotherapy. J Immunother, 2000, 23(4):412-418.
  • 5Miller PW,Sharma S, Stolina M, et al. Interatumoral administration of adenoviral interleukin 7 gene modified dendritic cellsaugments specific antitumor immunity andachieves tumor eradication.Human Gene Therapy,2000,11 (1): 53-65.
  • 6De Bruijn ML,Schuurhuis DH, Vierboom MP, et al. Immunization with human papillomavirus Type16 ( HPV16 ) oncoprotein-loaded dendritic cells as well as protein inadjuvant induces MHC class I-restricted protection to HPV16-induced tumor cells. Cancer Researc
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同被引文献36

  • 1胡伟,顾美皎.子宫颈癌及癌前病变与性传播疾病关系的研究[J].中华妇产科杂志,1995,30(9):547-549. 被引量：28
  • 2陶萍萍,卞美璐,李敏,刘军.HPV多重感染与宫颈病变关系探讨[J].中国妇产科临床杂志,2006,7(2):94-96. 被引量：112
  • 3赵奕,徐宝甜.人乳头瘤病毒基因与宫颈癌关系研究进展[J].国际检验医学杂志,2006,27(6):516-517. 被引量：12
  • 4李明成,郑华.尖锐湿疣患者人乳头瘤病毒感染基因型的检测[J].北华大学学报（自然科学版）,2007,8(2):118-120. 被引量：5
  • 5Castellsague X, Diaz M, De Sanjose S, et al. Worldwide human papillomavirus etiology of cervical adenocarcinoma and its cofactors:implications for screening and prevention. Journal of the National Cancer Institute, 2006,98 ( 5 ) : 303-315.
  • 6Franceschi S. The IARC commitment to cancer prevention the example of papilomavirus and cervical cancer. Recent Results Cancer Research, 2005,116 ( 10 ) : 277-297.
  • 7Clavel C, Masure M, Bory JP, et al. Human papillomavirus testing in primary sereening for the detection of high-risk lesion astudy of 7932 woman. Bridsh Journal of Cancer,2001,89 (8) : 1616-1623.
  • 8Howard M, Sellors Kaczorow . Optimizing the hyrid capture 11human Da-Dillomavims test to test to detect cervical intraepithe- lial neoplasia . Obstet Gyneeol, 2002, 10 (5) :972-980.
  • 9Eiben GL, Da Silva DM, Fausch SC, et al. Cervical cancer vaccines: recent advances in HPV research. Viral Immunology,2003, 16(2) :111-121.
  • 10Munoz N, Bosch FX, Castellsague X, et al. Againstwhich human papillomavirus types shall we vaccinate and screen The international per-spective. International Journal of Cancer ,2004,111 (6) :278.

引证文献3

二级引证文献14

国外医学（病毒学分册）
2004年 第6期

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