摘要
瘦蛋白 (leptin)是由肥胖基因编码、脂肪细胞分泌的一种分子量为 16kDa的蛋白质 ,是一种重要的代谢调节信号 ,对人和动物的采食量、能量代谢、繁殖性能等具有重要调节功能 ,对人肥胖病的治疗和改善动物的生产性能、胴体组成等有良好的潜在应用前景 .主要概述了瘦蛋白基因的克隆、转录。
Leptin is a 16-kDa protein encoded by ob gene and secreted from adipoc ytes, and is thought to be a metabolic signal that regulates food intake, energy expenditure and balance and reproductive function in human and animals. It has potential application in drug therapies for human obesity and improvement of pro ductive efficiency and carcass composition in animals. This paper mainly deals w ith the cloning, transcription and expression regulation of leptin gene, leptin receptors and its signal transduction. [
出处
《昆明医学院学报》
2004年第F12期104-107,共4页
Journal of Kunming Medical College
基金
云南省自然科学基金资助项目 (2 0 0 2C0 0 4 5M)
