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沙利度胺联合化疗治疗难治性多发性骨髓瘤 被引量:3

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摘要 目的:观察沙利度胺联合化疗治疗难治性多发性骨髓瘤(MM)的疗效及其副作用。方法:5例患者均给予沙利度胺联合化疗,沙利度胺的剂量为400mg/d~800mg/d,根据血清M蛋白和骨髓瘤细胞的减少判断疗效。结果:总有效率为80%无不能耐受的毒副作用。结论:沙利度胺联合化疗可作为难活性多发性骨髓瘤有效的治疗方法。
出处 《白血病.淋巴瘤》 CAS 2004年第6期351-352,共2页 Journal of Leukemia & Lymphoma
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  • 1Hales B. Thalidomide on the comeback trail [J]. Nat Med, 1999, 5:489.
  • 2Singhal S, Mehtu J, Desikan R, et al. Antitumor activity of thalidomide in refractory multiple myeloma[J]. N Engl J Med, 1999,341(21):1565.
  • 3Raje N R, Anderson K. Thalidomide a revival story [J]. N Engl J Med, 1999, 341:1606.
  • 4Teosk, Sabourin P J, O'Brien K, et al.Metabolism of thalidomide in human microsomes.cloned human cytochrome p-450isozymes.and Hansen' disease patients[J]. J Biochem Mol Toxicol, 2000, 14(3):140-147.

同被引文献24

  • 1张卫平,郑翠苹,王肖岚,徐杰.反应停联合M_2方案治疗难治性复发性骨髓瘤18例疗效分析[J].肿瘤研究与临床,2004,16(3):179-179. 被引量:4
  • 2胡喜梅,徐洪,周水阳,倪君,张红,何桂钧,朱碧辉.沙利度胺治疗原发性巨球蛋白血症疗效观察[J].白血病.淋巴瘤,2004,13(5):301-302. 被引量:3
  • 3[1]Singhal S,Mehta J,Desikan R,et al.Antitumor activity of thalidomide in refractory multiple myeloma[J].N Engl J Med,1999,341(21):1565-1571.
  • 4[3]Rajkumar SV,Kyle RA.Angiogenesis in multiple myeloma[J].Semin On-col,2001,28(6):560-564.
  • 5[4]Giovanni G.Michelle E,Letizia C,et al.Safety and efficiency of the thalindomide in patients with myeloid metaplasia[J].Br J Haematol,2001,114(4):78-83.
  • 6[5]Mesa RA,Steensma DP,PardananiA,et al.A phase 2 trial of combination low-dase thalidomide and prednisone foe the treatment of myelofibrosis with myeloid melaplasia[J].Blood,2003,101(7):2534-2541.
  • 7[7]Lisak L,Tahir S,Ahmed U,et al.Hematologic response to proteasome in-hibitor bortecomib in patients with myelodysplastic syndromes[J].Leuk Res,2003,27(suppl 1):S108.
  • 8[8]Dimopoulos MA,Tsatalas C,Zomas A,et al.Treatment of Waldenstrom's mcroglobulinemia with single-agent thalidomide or with combination of clarithromycin,thalidomide and dexamelhasone[J].Semin Oncnl,2003,30(2):265-269.
  • 9[10]Vogelsang GB,Farmer ER,Hess AD,et al.Thalidomide for thet reatment of chronict grofc-versus-host disease[J].N Engl J Med,1992,326(16):1055.
  • 10[11]Koc S,Leisenring W,Flowers ME.Therapy for chronig grafc-ver-sus-host disease:a randomized trial comporing cyclosporine phls pred-nisone versus prednisone alone[J].Blood,2000,96(12):3995.

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