摘要
AIM:To study the effect of anhydro-3-sulphopropyl-3′-sulphoethyl-5,5′-diphenyl-9-ethyl-oxacarbocyanine hydroxide (B1143) in photodynamic therapy.METHOD: The growth rate of KB cells inhibited by B1143 was tested by Trypan blue exclusion assay and 7-AAD stain assay was used to test the death rate of KB cells induced by B1143.RESULT: B1143 could inhibit the growth of KB cells and induce KB cells to death.CONCLUSION: B1143 is promising to be used in photodynamic therapy as a photosensitizer.
AIM:To study the effect of anhydro-3-sulphopropyl-3′-sulphoethyl-5,5′-diphenyl-9-ethyl-oxacarbocyanine hydroxide (B1143) in photodynamic therapy.METHOD: The growth rate of KB cells inhibited by B1143 was tested by Trypan blue exclusion assay and 7-AAD stain assay was used to test the death rate of KB cells induced by B1143.RESULT: B1143 could inhibit the growth of KB cells and induce KB cells to death.CONCLUSION: B1143 is promising to be used in photodynamic therapy as a photosensitizer.
出处
《中国药科大学学报》
CAS
CSCD
北大核心
2004年第6期587-589,共3页
Journal of China Pharmaceutical University
基金
中国科学院化学研究所分子动态与稳态结构国家重点实验室开发基金([2002]09)~~
